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Effect and Mechanism of Ethyl 3，4-Dihydroxybenzoate from Artemisia capillaris Thunb. Aerial Part on Non-Alcoholic Steatohepatitis
更新时间：2024-04-27
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    • Effect and Mechanism of Ethyl 3，4-Dihydroxybenzoate from Artemisia capillaris Thunb. Aerial Part on Non-Alcoholic Steatohepatitis

    • “本研究从中药茵陈中筛选出具有显著抗氧化活性的成分原儿茶酸乙酯（EDHB），并通过体外和体内实验验证了其对非酒精性脂肪性肝炎（NASH）的治疗作用。研究结果显示，EDHB能有效改善NASH大鼠的肝组织病理变化，减轻脂肪变性，降低肝脏转氨酶水平，抑制肝脏炎症因子的表达及转录。这一研究成果不仅为NASH的治疗提供了新的药物候选，也为中药资源的开发利用提供了新的思路。同时，该研究也为抗氧化活性成分的筛选和药效评价提供了新的方法和手段，对于推动中药现代化和国际化具有重要意义。”
      ”
    • J Wuhan Univ （Nat Sci Ed）   Vol. 70, Issue 2, Pages: 177-185(2024)

    • DOI：10.14188/j.1671-8836.2022.0299    

      CLC： R96

    • Published：24 April 2024，

      Received：13 December 2022，

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  • SHEN Wanying，WEI Xiaofang，YAO Jie，et al.Effect and Mechanism of Ethyl 3，4-Dihydroxybenzoate from Artemisia capillaris Thunb. Aerial Part on Non-Alcoholic Steatohepatitis ［J］.J Wuhan Univ （Nat Sci Ed），2024，70（2）：177-185. DOI：10.14188/j.1671-8836.2022.0299（Ch）. DOI：

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